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Additional radiotherapy to breast-conserving surgery is an optional treatment for de novo stage IV breast cancer: A population-based analysis.

Cancer Med · 2021 · PMC7940213 · PMID 33586323

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highly significantno p-value reported
Therefore, cooperative multidisciplinary care is highly significant in the management of de novo stage IV breast carcinoma, and the addition of RT to BCS might be the optimal treatment mode.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.