highly significantp < 1 × 10 −308
Finally, introns and lincRNAs have a more tolerant gwRVIS score distribution that more closely resembles the distribution from intergenic regions, but due to the sheer size of the corresponding score lists the divergence remains highly significant (median scores: −0.050, −0.0015; Mann–Whitney U vs. intergenic: p < 1 × 10 −308 and p = 2.6 × 10 −168 , respectively).