Effect of experimental orthodontic pain on gray and white matter functional connectivity.

CNS Neurosci Ther · 2021 · PMC7941220 · PMID 33369178

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highly significantno p-value reported

Numerous studies have shown that pain can produce highly significant changes in brain structure and function.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.