Current status on microsatellite instability, prognosis and adjuvant therapy in colon cancer: A nationwide survey of medical oncologists, colorectal surgeons and gastrointestinal pathologists.

In 31 of 47 non‐overlapping studies reported in two meta‐analysis on MSI and prognosis in colorectal cancer, there was no statistically significant difference or only marginal significance. 1 , 2 The benefit associated with chemotherapy in Stage II colon cancer is small, and decision‐making in patients with Stage II colon cancer is often individualised to patient's preferences and comorbidities.

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