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Linking bacterial enterotoxins and alpha defensin 5 expansion in the Crohn's colitis: A new insight into the etiopathogenetic and differentiation triggers driving colonic inflammatory bowel disease.

PLoS One · 2021 · PMC7942995 · PMID 33690604

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an increasing trendno p-value reported
Hospital admission rates and costs for IBD show an increasing trend assessed by specific pharmaceutical and disease features [ 15 – 19 , 21 – 26 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.