The Combination of Sonographic Features and the Seven-Gene Panel May be Useful in the Management of Thyroid Nodules With Indeterminate Cytology.

Front Endocrinol (Lausanne) · 2021 · PMC7943869 · PMID 33716969

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.1000

boldest claim

The sentences

a trend toward significancep = 0.08so close (0.05 < p ≤ 0.1)

In detail, 100% of low risk US nodules were benign at histology, while the rate of malignancy in high risk US nodules was only 21.4%, with a trend toward significance ( p = 0.08).

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fell just short of statistical significancep = 0.10so close (0.05 < p ≤ 0.1)

The cancer rate was higher in US high risk nodules (48.7 versus 29.9% in low-risk US nodules) but this difference fell just short of statistical significance ( p = 0.10), probably due to the small cohort of indeterminate thyroid nodules submitted to surgery.

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