Exon 20 YVMA insertion is associated with high incidence of brain metastasis and inferior outcome of chemotherapy in advanced non-small cell lung cancer patients with HER2 kinase domain mutations.

Transl Lung Cancer Res · 2021 · PMC7947396 · PMID 33718019

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0.0640

closest p · 1.3× alpha

0.0640

boldest claim

The sentences

marginal significanceP=0.064so close (0.05 < p ≤ 0.1)

While for cumulative brain metastasis incidence, YVMA insertion also associated with higher incidence of 12-month brain metastasis incidence as 24.4% compared with 3.6% in the non-YVMA group with marginal significance (P=0.064).

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