The SARS-CoV-2 Y453F mink variant displays a pronounced increase in ACE-2 affinity but does not challenge antibody neutralization.

2 A ) and a tight linear relationship ( R 2 = 0.9430) with a highly significant correlation ( ρ = 0.9711, p < 0.0001) of the serum antibody inhibition capacity to both RBD variants ( Fig. 2 B ).

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