marginal significanceP = 0.06
Ignoring AT neutral substitutions (AT→TA and CG→GC), only 26 of 84 singletons decrease AT content, compared with 17 of 34 high-frequency SNVs (marginal significance with Fisher’s exact test, P = 0.06).
Ignoring AT neutral substitutions (AT→TA and CG→GC), only 26 of 84 singletons decrease AT content, compared with 17 of 34 high-frequency SNVs (marginal significance with Fisher’s exact test, P = 0.06).