Abatacept enhances blood regulatory B cells of rheumatoid arthritis patients to a level that associates with disease remittance.

We have also noticed an increasing trend in levels of these Tregs in the blood of remitted patients, defined as DAS28-CRP < 2.6, although not to a significant level (Fig. 1 E; P = 0.525, and Fig. 1 F; P = 0.553, for LAG3 + cTreg and LAG3 + uTreg, respectively).

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