Outcomes in Guideline-Based Class I Indication Versus Earlier Referral for Surgical Myectomy in Hypertrophic Obstructive Cardiomyopathy.

The findings of Cox multivariable survival analysis for the primary composite outcome, in the subgroup excluding patients with documented obstructive coronary artery disease, were similar as follows (total n=2046, number of primary composite events=210): Age (for every 10‐year increase, HR, 1.60; 95% CI, 1.42, 1.90, P <0.001) and Class I indication versus earlier surgery (HR, 1.71; 95% CI, 1.18, 2.46, P <0.001) were associated with increased longer‐term primary composite events, while female sex was only borderline significant (HR, 1.26; 95% CI, 0.94, 1.73, P =0.089).

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