LncRNA GATA3‑AS1‑miR‑30b‑5p‑Tex10 axis modulates tumorigenesis in pancreatic cancer.

Oncol Rep · 2021 · PMC7962099 · PMID 33760161

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a decreasing trendno p-value reported

Furthermore, compared with the GATA3-AS1 + miR-30b-5p group, the cell viability and proliferation, invasion, and spheroid formation abilities once more exhibited a rising trend, and cell apoptosis exhibited a decreasing trend in the GATA3-AS1 + miR-30b-5p + Tex10 group ( Fig. 5B-F ).

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an increasing trendno p-value reported

The increased cell viability and proliferation, cell invasion, and stemness induced by GATA3-AS1 overexpression were all suppressed by the co-overexpression of GATA3-AS1 and miR-30b-5p; whereas the cell survival revealed an increasing trend with co-overexpression of GATA3-AS1, miR-30b-5p, and Tex10.

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