highly significantp < 0.0001
As shown in Additional file 1 : Figure S1, the correlation of eGDR calculated using this formula with glucose disposal rate (GDR) measured with euglycaemic-hyperinsulinemic clamp in 140 T2D patients was highly significant ( r = 0.624; p < 0.0001); moreover, it was higher than that of Homeostasis Model Assessment – Insulin resistance (HOMA-IR) in the 85 patients with calculable values ( r = 0.441; p < 0.0001) and similar to that reported in the validation study in T1D individuals [ 25 ].