Protein-loss of SWI/SNF-complex core subunits influences prognosis dependent on histological subtypes of intra- and extrahepatic cholangiocarcinoma.

Oncol Lett · 2021 · PMC7968003 · PMID 33747206

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Our current data give strong evidence, that IHC proven protein-loss of SWI/SNF core subunits (namely ARID1A-, BRG1-, BRM-, PBRM-1and INI1) is associated with a highly significant worse survival of small duct and large duct ICCA, whereas no significant change in survival for ECCA was detected.

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