Formulation development of itraconazole PEGylated nano-lipid carriers for pulmonary aspergillosis using hot-melt extrusion technology.

Int J Pharm X · 2021 · PMC7973123 · PMID 33748741

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a decreasing trendno p-value reported

The formulation exhibited a non-Newtonian behavior and showed a decreasing trend with the application of higher shear. 3.8 Nebulization of the ITZ-PEG-NLC Before nebulization of the formulation using the Philips Respironics Sami the Seal Nebulizer Compressor, the particle size was 101.20 ± 1.69 nm with a PDI of 0.26 ± 0.02.

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