Plasma cell marker, immunoglobulin J polypeptide, predicts early disease-specific mortality in HPV+ HNSCC.

J Immunother Cancer · 2021 · PMC7978288 · PMID 33737336

Europe PMC DOI

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0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

trending toward significancep=0.057so close (0.05 < p ≤ 0.1)

A multivariate Cox regression model, including key clinical covariates, showed that the top performing CD8+ T cell functionality signature, cytolytic, was an independent prognostic biomarker for OS (HR: 5.0, 95% CI: 1.1 to 1.23; p=0.041) and trending toward significance for DSS (HR: 4.6, 95% CI: 0.96 to 23; p=0.057) ( table 1 ).

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