The lncRNA XIST/miR-125b-2-3p axis modulates cell proliferation and chemotherapeutic sensitivity via targeting Wee1 in colorectal cancer.

Cancer Med · 2021 · PMC7982616 · PMID 33666372

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might be significantno p-value reported

Consequently, miR‐125b‐2‐3p could reverse the chemotherapeutic resistance of CRC cells, and this finding might be significant for clinical treatments for CRC. 4 DISCUSSION Currently, low chemotherapeutic efficiency and drug resistance remain the most substantial problems in clinical treatments, especially for advanced CRC patients, who might mainly depend on chemotherapeutic treatments.

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