Barely Significant
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The APOE ε4 exerts differential effects on familial and other subtypes of Alzheimer's disease.

Alzheimers Dement · 2020 · PMC7984370 · PMID 32881347

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an increasing trendno p-value reported
This study revealed that the APOE ε4 positive genotype was associated with different AD subtypes and showed an increasing trend in NC, FAD ( PSENs/APP ), SAD, and FAD (unknown) groups, in that order.

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