TMAO: a potential mediator of clopidogrel resistance.

Sci Rep · 2021 · PMC7985207 · PMID 33753834

Europe PMC DOI

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0.0590

closest p · 1.2× alpha

0.1390

boldest claim

The sentences

an increasing trendP = 0.059so close (0.05 < p ≤ 0.1)

Platelet aggregation Compared with the IR group, the clopidogrel + IR group had lower MaxAR-ADP (9.65 ± 5.60% vs 75.52 ± 14.99%, P < 0.05) and AveAR-ADP values (13.22 ± 5.81% vs 71.32 ± 16.66%, P < 0.05) and showed an increasing trend for MaxAT-ADP (447.67 ± 49.45 s vs 374.83 ± 67.81 s, P = 0.059); the TMAO + clopidogrel + IR group had lower MaxAR-ADP (35.05 + 24.93%, P < 0.05) and AveAR-ADP values (25.50 + 18.60%, P < 0.05).

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a decreasing trendP = 0.139not close (p > 0.1)

Compared with that in the clopidogrel + IR group, the tail bleeding time showed a decreasing trend in the TMAO + clopidogrel + IR group (10.5 min ± 8.63 min, P = 0.139) (Fig. 2 ).

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