A Dual Systems Genetics Approach Identifies Common Genes, Networks, and Pathways for Type 1 and 2 Diabetes in Human Islets.

The identified molecular and cellular processes included “Cell-to-cell signaling and interaction,” “Cell cycle,” “Cell morphology,” and “Lipid metabolism.” We also performed ClueGO pathway analysis of the “T1D-T2D islet eQTL interaction network” which identified 10 highly significant pathways that grouped into 5 clusters (Figure 1 in Supplementary File 1 ).

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