Nicotine abolishes memory-related synaptic strengthening and promotes synaptic depression in the neurogenic dentate gyrus of miR-132/212 knockout mice.

Addict Biol · 2021 · PMC7988623 · PMID 32293776

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Mixed‐effects ANOVA analysis showed a significant effect of time ( **** P < 0.0001, F 14,140 = 13.02), no significant effect of the genotype ( ns P = 0.1975, F 1,10 = 1.906), no significant genotype × treatment interaction ( ns P = 0.1926, F 1,10 = 1.952) and highly significant time × genotype × treatment interaction ( **** P < 0.0001, F 14,110 = 4.085; Figure 3C,D ).

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