Barely Significant
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Clinical Pharmacokinetics and Pharmacodynamics of Cerliponase Alfa, Enzyme Replacement Therapy for CLN2 Disease by Intracerebroventricular Administration.

Clin Transl Sci · 2021 · PMC7993266 · PMID 33202105

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a slight trendno p-value reported
There was a slight trend of increasing plasma C max with decreasing age but was not exhibited of plasma AUC 0–t ( Figure 3 ).

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