Idiosyncratic Drug-Induced Liver Injury: Mechanistic and Clinical Challenges.

Int J Mol Sci · 2021 · PMC7998339 · PMID 33799477

Europe PMC DOI

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may not be significantno p-value reported

Even though drug covalent binding is easy to detect with a good anti-drug antibody, the absolute amount of covalent binding is very small, and it may not be significant relative to other causes of unfolded protein such as viral infections [ 132 ].

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