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Perioperative Pain Management and Opioid Stewardship: A Practical Guide.

Healthcare (Basel) · 2021 · PMC8001960 · PMID 33809571

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may not be significantno p-value reported
Caution may still be warranted with selective COX-2 inhibitors in noncardiac surgery patients with significant cardiovascular disease, but these risks may not be significant when exposure is limited to short-term perioperative use [ 183 , 212 , 223 , 224 , 225 ].

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