Integration of Data from Liquid-Liquid Phase Separation Databases Highlights Concentration and Dosage Sensitivity of LLPS Drivers.

Int J Mol Sci · 2021 · PMC8002189 · PMID 33809541

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highly significantno p-value reported

To verify that the observed highly significant enrichment for haploinsufficient genes or ohnologs is not due to an enrichment of LLPS drivers for transcription factors, we evaluated the enrichment for TFs in the LLPS-associated dataset, using the same dataset of transcription factors as in Reference [ 122 ] (a list of 1639 TFs originally published in Reference [ 128 ]).

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