The “Indirect Lipid index” ratio (IL, A1450 cm −1 /A1668 cm −1 ) showed an increasing trend, with significant differences found only between mild and severe radiological OA (K-L II vs.
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Optical Biomarkers for the Diagnosis of Osteoarthritis through Raman Spectroscopy: Radiological and Biochemical Validation Using Ex Vivo Human Cartilage Samples.
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