The 35th Anniversary of the Discovery of EPR Effect: A New Wave of Nanomedicines for Tumor-Targeted Drug Delivery-Personal Remarks and Future Prospects.

J Pers Med · 2021 · PMC8004895 · PMID 33810037

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almost insignificantno p-value reported

In conclusion, passive targeting only showed a short period of tumor retention, which is almost insignificant compared to the prolonged time of drug retention seen in EPR driven tumor delivery of macromolecular anti-cancer agents.

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