Cognitive Impairment After Resolution of Hepatic Encephalopathy: A Systematic Review and Meta-Analysis.

Front Neurosci · 2021 · PMC8006450 · PMID 33790729

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In the first analysis, the comparison between the OHE and NHE groups unveiled a robust, highly significant deleterious effect of OHE history on cognitive function in cirrhotic patients, yielding a pooled Std Mean Difference [95% CI] of −0.72 [−0.94 to −0.50] ( Z = 6.38, P < 0.00001, n = 12) ( Figure 2 ).

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