Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease.

Am J Hum Genet · 2021 · PMC8008495 · PMID 33600772

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highly significantno p-value reported

Highly significant overall overlap of common variant risk for inflammatory bowel disease susceptibility between individuals with African and European ancestries was observed, with 41 of 241 previously known lead variants replicated and overall correlations in effect sizes of 0.68 for combined inflammatory bowel disease.

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