A decreasing trend was observed on IL-17 and RORγt expressions by CD4 + CD25 + T cells ( Figure 5A ).
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The sentences
RvE1 decreased the frequency of CD4 + CD25 + cells, but in contrast with its effect gated on only CD4 + cells, there was an increasing trend on IL-17 + and RORγt + cells in response to RvE1 with no statistical significance ( Figure 2C ).