Plasmid-Chromosome Crosstalk in <i>Staphylococcus aureus</i>: A Horizontally Acquired Transcription Regulator Controls Polysaccharide Intercellular Adhesin-Mediated Biofilm Formation.

Front Cell Infect Microbiol · 2021 · PMC8019970 · PMID 33829001

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highly significantno p-value reported

Biofilm testing revealed a highly significant reduction of PIA production when icaADBC pAF was combined with icaR RN , suggesting that IcaR from S. aureus RN4220 is indeed able to repress the icaADBC pAF genes from pAFS11 ( Figure 4C ).

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