Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors.

Mol Oncol · 2021 · PMC8024740 · PMID 33513287

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did not achieve significanceno p-value reported

Moreover, anti‐correlations were maintained when stratified analysis per NS histology was performed (in categories with sufficient number of patient samples, Table S3 ): when considering only pure ECs or only Mixed Tumors, the significant anti‐correlation between methylation and expression was maintained for all genes (except for PALB2 in pure ECs, which did not achieve significance).

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