Deconvolution of intergenic polymorphisms determining high expression of Factor H binding protein in meningococcus and their association with invasive disease.

Interestingly, the expression levels were significantly predictive of the invasive disease by the ANOVA test, with a median p -value of 2.3 X 10 −86 (ranging from 1.5 X 10 −98 to 2.0 X 10 −76 ), reflecting a positive trend in the proportion of invasive strains with higher predicted expression levels for fHbp.

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