The evolving obesity challenge: targeting the vagus nerve and the inflammatory reflex in the response.

Pharmacol Ther · 2021 · PMC8027699 · PMID 33310156

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highly significantno p-value reported

VNS treatment for 2 years of patients with treatment-resistant depression also results in highly significant weight loss without additional dieting or exercising ( Pardo et al., 2007 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.