Aberrant TGF-β1 signaling activation by MAF underlies pathological lens growth in high myopia.

Nat Commun · 2021 · PMC8032689 · PMID 33833231

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a decreasing trendno p-value reported

As previous studies have demonstrated a decreasing trend of α-crystallins, a type of small heat shock proteins, in the lens of highly myopic eyes 17 , 18 , it stands to reason that the larger lens in high myopia might be related to changes of β/γ-crystallins.

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