Barely Significant
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AB016. A double-blind, placebo-controlled, phase 2 trial of a novel toll-like receptor 7/8/9 antagonist (IMO-8400) in dermatomyositis

Annals of Translational Medicine · 2021 · PMC8033384

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a positive trendno p-value reported
We found an association between CDASI and skin IFN signature scores (β=12.9, P=0.0002), an association between 5-D Itch Scale and skin IFN signature scores (Rho =0.65, P<0.0001), a lack of association between 5-D Itch Scale and blood IFN signature scores (Rho =0.22, P=0.24), and a positive trend that did not reach significance between CDASI and 5-D Itch Scale scores.

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