Assessment of γ-H2AX and 53BP1 Foci in Peripheral Blood Lymphocytes to Predict Subclinical Hematotoxicity and Response in Somatostatin Receptor-Targeted Radionuclide Therapy for Advanced Gastroenteropancreatic Neuroendocrine Tumors.

Cancers (Basel) · 2021 · PMC8036952 · PMID 33806081

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0570

boldest claim

The sentences

highly significantp < 0.0001actually significant

There was a highly significant correlation between γ-H2AX and 53BP1 foci in LCLs ( r = 0.9761 (95% CI, 0.9533 to 0.9878), p < 0.0001) and PBLs ( r = 0.9883 (95% CI, 0.9683 to 0.9957), p < 0.0001). 2.2.

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borderline significantp = 0.0570so close (0.05 < p ≤ 0.1)

Consistently, there was a borderline significant association between % change in SSR-TV and % 53BP1 + cells at baseline ( r = 0.4215, p = 0.0570) and % change in 53BP1 + cells between BL and +24 h ( r = −0.3866, p = 0.0834) in correlation analysis.

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