Insights into the Role of the Microbiota and of Short-Chain Fatty Acids in Rubinstein-Taybi Syndrome.

Int J Mol Sci · 2021 · PMC8037970 · PMID 33807238

Europe PMC DOI

hedged sentences

0.0100

closest p · 0.2× alpha

0.0741

boldest claim

The sentences

highly significantp < 0.01actually significant

All the compounds succeeded in boosting histone acetylation in RSTS LCLs compared to healthy donor (HD) LCLs, with VPA exposure resulting highly significant ( p < 0.01).

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a decreasing trendp = 0.0741so close (0.05 < p ≤ 0.1)

A decreasing trend in butyrate content was observed (4.13 ± 1.40 vs. 5.14 ± 1.79 mg/g feces, p = 0.0741, Mann–Whitney test), whereas acetate, propionate, and branched-chain fatty acids (iso-butyrate and iso-valerate) concentrations were similar ( p = 0.194, p = 0.874, p = 0.786, and p = 0.467, respectively).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.