Consistent with our previous observations, 31 human primary TM cell cultures incubated in the presence of TGF-β2 exhibit markedly significant increases in the expression and release of collagens I and collagens IV proteins when analyzed by immunoblot (data not shown) or in situ by immunocytochemistry ( Fig. 7 ).
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TGF-β2 Promotes Oxidative Stress in Human Trabecular Meshwork Cells by Selectively Enhancing NADPH Oxidase 4 Expression.
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