The safety and immunogenicity of an inactivated SARS-CoV-2 vaccine in Chinese adults aged 18-59 years: A phase I randomized, double-blinded, controlled trial.

An increasing trend of neutralizing antibodies was observed starting from day 7 after booster immunization, with seroconversion rates of 54.2% (low-dose), 79.2% (medium-dose) and 69.6% (high-dose) and GMTs of 4.2, 11.2 and 8.9 ( Fig. 4 b).

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However, there appeared to be a decreasing trend in the neutralizing antibody titers from day 14 to day 28 ( Fig. 4 a).

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