Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth.

Elife · 2021 · PMC8041465 · PMID 33843586

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an overall trendno p-value reported

When comparing TNs to NNs we found an overall trend toward fewer amino acid changes in the CDRs of TNs (maximum likelihood estimate of ω CDR in Figure 3C ) indicating stronger purifying selection.

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