Genomics-Guided Drawing of Molecular and Pathophysiological Components of Malignant Regulatory Signatures Reveals a Pivotal Role in Human Diseases of Stem Cell-Associated Retroviral Sequences and Functionally-Active hESC Enhancers.

Front Oncol · 2021 · PMC8044830 · PMID 33869024

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highly significantno p-value reported

Highly significant associations ( Supplemental Tables S9 , S10 ) of genes defining human embryonic, neurodevelopmental, and cancer survival predictors’ transcriptional networks with naïve ( Supplemental Table S9 ) and primed ( Supplemental Table S10 ) hESC functionally active enhancers have been observed.

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