Barely Significant
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Association between metabolic and hormonal profile, proinflammatory cytokines in saliva and gingival health in adolescent females with polycystic ovary syndrome.

BMC Oral Health · 2021 · PMC8045362 · PMID 33849511

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might be significantno p-value reported
Finally, there is increasing evidence in the literature that psychosocial stress, depression, and anxiety might be significant risk factors of periodontal disease [ 62 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.