highly significantp < 0.0001
Nevertheless, subgroup analysis revealed highly significant sex-related differences between good, moderate, and unfavorable HRQoL outcomes ( p < 0.0001) (Fig. 2 ), as 68.6% of males reported good, 15.7% moderate, and 15.7% unfavorable HRQoL, while only 51.5% females stated good, 33.3% moderate, and 15.2% unfavorable HRQoL up to 10 years after TBI (Fig. 3 ).