Primary and secondary clarithromycin resistance in Helicobacter pylori and mathematical modeling of the role of macrolides.

Nat Commun · 2021 · PMC8050269 · PMID 33859206

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marginal significanceno p-value reported

Thus, spontaneous mutation seems to have only marginal significance in the origin of primary Cla-res cases compared to the spread of resistant strains.

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