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Inferring molecular mechanisms of dexamethasone therapy in severe COVID-19 from existing transcriptomic data.

Gene · 2021 · PMC8054526 · PMID 33887367

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an overall trendno p-value reported
Clustering of these DEGs revealed, as expected, an overall trend for opposite gene regulation between cytokines as a whole and anti-cytokine/anti-inflammatory agents as a whole, with the former group mimicking COVID-19 associated gene regulation and the latter dexamethasone associated ( Fig. 1 G ).

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