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Exploring SARS-COV-2 structural proteins to design a multi-epitope vaccine using immunoinformatics approach: An in silico study.

Comput Biol Med · 2021 · PMC8055380 · PMID 33895459

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an increasing trendno p-value reported
The RMSD value of TLR4 had an increasing trend at the beginning of the simulation period and reached 0.6 nm after 17000 ps, and then decreased to 0.3 nm in 24,000 ps After this time, the RMSD value increased to approximately 0.4 nm and remained constant until the end of the simulation time.

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