Evidence-Based Guidelines and Secondary Meta-Analysis for the Use of Transcranial Direct Current Stimulation in Neurological and Psychiatric Disorders.

Patients with malformations of cortical development had a trend towards seizure reduction (by 56% 1 month later) and marginally significant ED reduction following cathodal tDCS ( Fregni et al., 2006f ).

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Quantitative analysis of 5 studies shows a barely significant ES of −0.62 (95% confidence interval [CI] = −1.23, −0.01) in favor of tDCS, primarily influenced by the favorable results of 1 study ( Khedr et al., 2017a ); there is significant and substantial heterogeneity (I 2 = 68.2%, P = .013) ( Table 12 ; supplemental Figure 1a ). tDCS in Migraine — Anodal

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