Beyond association: successes and challenges in linking non-coding genetic variation to functional consequences that modulate Alzheimer's disease risk.

Mol Neurodegener · 2021 · PMC8061035 · PMID 33882988

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highly significantno p-value reported

have recently conducted a GWAS using self-reported parental history of AD (i.e., AD-by-proxy) and undertook SMR integrating with eQTL and meQTL data from dorsolateral prefrontal cortex, identifying highly significant associations with expression of CR1 , TOMM40 and KAT8 amongst other genes [ 46 ].

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