Safety, pharmacokinetics and exploratory pro-cognitive effects of HTL0018318, a selective M<sub>1</sub> receptor agonist, in healthy younger adult and elderly subjects: a multiple ascending dose study.

Alzheimers Res Ther · 2021 · PMC8061066 · PMID 33883008

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an apparent trendno p-value reported

There were no chemistry blood results that showed an apparent trend toward increased incidence with ascending dose levels of HTL0018318 during the study.

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